Intrapocket irrigations with tetracycline HCI solution part II : microbiological effects

Intrapocket irrigations with tetracycline HCI solution part II : microbiological effects

Chanin Taechaprasertvittaya, D. of Periodontology, F. of Dentistry, Chulalongkorn U., Bangkok
Soramitz Pisuithanakan, D. of Conservative Dentistry, F. of Dentistry, PSU.
Boontida Chotichanapibal, Department of Dentistry, Aviation Medicine, Royal Thai Air Force, Bangkok

Published : J Dent Assoc Thai 1999, 49(6) : 361-368
Key words : subgingival irrigation, intrapocket irrigation, tetracycline hydrochloride, microbiological effect

The present study was undertaken to evaluate the efficacy of intrapocket irrigations with tetracycline hydrochloride (TTC-HCI) on the microbial parameters in the adjunctive treatment of adult periodontitis. Study design, patient and site selection, and treatment had described in part I. Microbiological assessment of the subgingival flora counts was transformed by the log₁₀ to stabilize the variance of the total count. Differences in counts of each microbial group on the difference treatments were determined by the nonparametric Kruskal-Wallis analysis of variance. Post hoc tests for significant rank differences were performed as described by the Mann-Whitney U test to compare between treatments and the Wilcoxon signed-rank test for within treatments. The difference between groups in increased the counts of coccoid cells was statistically significant between TC5 and SRP groups at the weeks 14 and weeks 28, and TC5 with SRP groups at the weeks 14. The difference between groups in decreasing the counts of motile rods was statistically significant between TC5 and vehicle groups at the weeks 14 and weeks 28, and decreased the counts of spirochetes between TC10 and SRP groups at the weeks 14 the proportions of coccoid cells were higher and those for spirochetes were lower within treatments at weeks 14 and weeks 28 when compared with baseline. In TC5 and vehicle groups, the proportions of nonmotile rods were higher at weeks 14 and weeks 28 when compared with the baseline.

This study demonstrated that repeated intrapocket irrigation as an adjunct to scaling and root planing resulted in the reduction of spirochetes and increasing coccoid cells when compared with the baseline.

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