Triterpenoids from Thai medicinal plant, Willughbeia firma
Sanan Subhadhirasakul, Assoc. Prof., D. of Pharmacognosy and Pharmaceutical Botany,
F. of Pharmaceutical Sci., PSU.
Hiromitsu Takayama, F. of Pharmaceutical Sciences, Chiba U., Chiba, Japan
Mariko Kitajima, F. of Pharmaceutical Sciences, Chiba U., Chiba, Japan
Norio Aimi, F. of Pharmaceutical Sciences, Chiba U., Chiba, Japan
Corresponding e-mail : ssanan@ratree.psu.ac.th
Grant : TRF
Published : Natural Medicines 2000, 54(3) : 155-157
Key words : triterpenoid, docosanoyl lupeol, Willughbeia firma, Apocynaceae
From the stems of Willughbeia firma Bl., collected in southern Thailand, a fatty acid ester of
a triterpenoid, 3-docosanoyl lupeol (1), was isolated as a major component along with lupeol and
acetyl lupeol. The structure of 1 was determined by spectroscopic analysis and by synthesizing 1
from natural lupeol and docosanoyl chloride.
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