Histologic comparison of Novak endometrial biopsy and uterine curettage
in the patients with abnormal uterine bleeding
Bongkoch Naraput, D. of Obstetrics and Gynaecology, F. of Medicine, PSU.
Chatpavit Getpook, Asst. Prof., D. of Obstetrics and Gynaecology, F. of Medicine, PSU.
Hutcha Sriplung, Assoc. Prof., D. of Pathology, F. of Medicine, PSU.
Alan Geater, Epidemiology Unit, F. of Medicine, PSU.
Presented : The 16th Annual Academic Meeting, Faculty of Medicine, PSU, Hat Yai, Songkhla,
16-18 August 2000
Key words : histologic comparison, Novak endometrial biopsy, uterine curettage,
uterine bleeding
Introduction : Abnormal uterine bleeding is the most common presenting symptom of the patients at Gynecologic clinic. In some cases histologic diagnosis is necessary. Although uterine cu-rettage is currently accepted as the standard method for pathologic diagnosis, it may be replaced by another method with less cost, well tolerate, and accepted diagnosis accuracy such as Novak endo-metrial biopsy. The purpose of this study was to compare the histologic results of endometrial tissue from Novak and from curettage.
Objective : To compare histologic results of endometrial tissue that obtained from Novak and from uterine curettage.
Study design : Comparative diagnostic test.
Study population : 225 patients scheduled for uterine curettage at Songklanagarind Hospital during Nov. 1999 - Jun. 2000.
Methods : We studied prospective 225 consecutive patients scheduled for uterine curettage. Endometrial biopsy with Novak instrument was performed before the curettage. The specimens from 2 methods were examined separately by a pathologist.
Results : In 179 cases (96.7%), the endometrial histologic results of curettage agreed with those Novak biopsy. All 3 cases of endometrial cancer were identified by both Novak biopsy and uterine curettage. True positive rate (TPR) of normal endometrium was 96.9-100% and positive predictive value (PPV) was 91.9-99%.
Conclusion : Our data suggested that with Novak endometrial biopsy in patients with abnormal uterine bleeding are highly accurate.
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