Effect of the leaf of Toei-hom (Pandanus odorus Ridl) on blood glucose in normal mice
ผลของสารสกัดใบเตยหอม (Pandanus odorus Ridl.) ต่อระดับน้ำตาลในเลือดของหนูปกติ

Rachawan Limviwatkul, Scientist, D. of Physiology, F. of Sci., PSU.
Weranut Nilnond, Assoc. Prof., D. of Physiology, F. of Sci., PSU.
Corresponding e-mail : nweranut@ratree.psu.ac.th

Grant : Faculty of Science, PSU.
Published : Research Report
Key words : blood glucose, Pandanus odorus, Toei-hom leaf, hyperglycemic effect

The effect of water extract of Toei-hom (Pandanus odorus Ridl.) leaves on blood glucose level was examined in normal mice. Blood glucose level of treated mice, to which the extract was orally administered at concentration of 0.25, 0.5, 1, 2 and 4 g/kg B.W. for 3 hours, was significantly higher than blood glucose level of control mice (P<0.05). Propranolol (0.6 mg/kg), a b-adrenoceptor antagonist, abolished the hyperglycemic effect of the extract at concentration 0.5 and 1 g/kg. In oral glucose tolerance test, the elevation of blood glucose level in treated mice was not significantly different from control mice. Additionally, oral administration of the extract at concentration of 0.25 g/kg for 7 days did not significantly affect blood glucose level. These results indicate that the water extract of toei-hom leaves has a hyperglycemic effect. The effect may be mediated by b-adrenoceptor in liver.

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